Location:Home > Technology

Technology

BioRegen Technology

BioRegen is the abbreviation of Biological Regeneration, and the technical concept is to repair the wound and reach the ultimate goal of reconstruction of physiological function with biological repair technology.

The BioRegen technology platform is based on the technology of advanced self-crosslinked & biomimetic biomaterials: create a microenvironment of extracellular matrix suited for cell growth, migration and differentiation using extracellular matrix material with biological function (e.g., glycosaminoglycan (sodium hyaluronate, etc.), collagen and growth factor, etc.) as raw material, with self cross-linking and biosimulation technique, which can help realize scar free healing of trauma tissue or tissue engineering of regeneration and healing, and reach the goal of reconstruction of physiological function.

The BioRegen technology platform has wide application, base on which a series of innovative biopharmaceutical materials have been successfully developed, so domestic gap in this field has been filled, and the clinical efficacy has reached internationally advanced level.


Clinical Studies

HyaRegen® Gel:


 ◆ A Randomized Controlled Trial on the Efficacy and Safety of a New Crosslinked Hyaluronan Gel in Reducing Adhesions after Gynecologic Laparoscopic Surgeries.


Liu et al.: JMIG. 2015; 22(5): 853-863.


 ◆ Effect of a new cross-linked hyaluronan gel on the staple line after sleeve gastrectomy in a rat model.


Bülbüller N et al.: Acta Cir Bras. 2018; 33(2): 163-184.


 ◆ Cross-linked hyaluronan gel inhibits the growth and metastasis of ovarian carcinoma.


Pang et al. Journal of Ovarian Research. 2018; 11:22.


 ◆ Cross-linked hyaluronic acid gel inhibits metastasis and growth of gastric and hepatic cancer cells: in vitro and in vivo studies.


Ting Lan et al.: Oncotarget. 2016; 7:40.

MateRegen® Gel


 ◆ A randomized multi-center controlled study on the efficacy and safety of a new crosslinked hyaluronan gel to prevent intrauterine adhesion following hysteroscopic adhesiolysis.


Xiao S. et al.: Giorn. It. Ost. Gin. 2015; XXXVII:4.


 ◆ New Crosslinked Hyaluronan Gel for the Prevention of Intrauterine Adhesions after Dilation and Curettage in Patients with Delayed Miscarriage: A Prospective, Multicenter, Randomized, Controlled Trial.


Li et al.: JMIG. 2018; 26(1):94-99.


 ◆ Using New-Crosslinked Hyaluronic Acid Gel to Prevent Intrauterine Adhesion after Hysteroscopic Septum Resection: A Prospective, Randomized, Controlled Study.


Tayfun KUTLU et al.: TJRMS. 2018; 2(2).


 ◆ Efficacy of a New Crosslinked Hyaluronan Gel in the Prevention of Intrauterine Adhesions.


Can S et al.: JSLS. 2018; 22:4.

PureRegen® Gel


 ◆ The evaluation of two new hyaluronan hydrogels as nasal dressing in the rabbit maxillary sinus.


Chen Q et al.: Am J Rhinol Allergy. 2012; 26(2):152-6.


 ◆ The clinical outcomes of new hyaluronan nasal dressing: A prospective, randomized, controlled study.



 Shiet al.: American Journal of Rhinology and Allergy. 2013; 27(1):71-76.



 ◆ Self-cross-linked hyaluronic acid hydrogel in ethmoidectomy: A randomized, controlled trial.


Keith E et al.:American Journal of Rhinology and Allergy. 2014; 28(6):508-513.


 ◆ The clinical outcomes of using a new cross-linked hyaluronan gel in endoscopic frontal sinus surgery.


T. Dal et al.: European Archives of Oto-Rhino-Laryngology. 2017; 274(6).


 ◆ Effectiveness of hyaluronic acid in post-tonsillectomy pain relief and wound healing: A prospective, double-blind, controlled clinical study.


D. Hancı et al.: International journal of pediatric otorhinolaryngology. 2015; 79(9).







技术平台

BioRegen Biomedical (Changzhou) Co., Ltd. 苏ICP备09086452号-1号